产品货号：
Z15580
中文名称：
DPYD抗体
英文名称：
Anti-DPYD Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DPYD Antibody |
| 指标别名 | DHP;DHPDHASE;Dihydrothymine dehydrogenase;Dihydrouracil dehydrogenase;DPD;DPYD |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | DPYD |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human DPYD(33-52aa AKKLDKKHWKRNPDKNCFNC),different from the related rat and mouse sequences by one amino acid. |
| 实际分子量 | 111KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DPYD(Dihydropyrimidine Dehydrogenase),also called DPD,is an enzyme that in humans is encoded by the DPYD gene.The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism.The structure of the DPYD gene contains 23 exons spanning about 950kb.Using somatic cell hybrid strategies,the DPYD gene is mapped to the centromeric region of chromosome 1 between 1p22 and 1q21.By fluorescence in situ hybridization,the DPYD gene is mapped to 1p22.The highest level of DPD was found in monocytes followed by that in lymphocytes,granulocytes,and platelets,whereas no significant activity of DPD could be detected in erythrocytes.The activity of DPD in peripheral blood mononuclear cells was intermediate between that observed in monocytes and lymphocytes.By cDNA microarray,Western blot analysis,and luciferase reporter assay,the transcription factor LSF was identified as a positive regulator of DPYD. |
| Uniprot ID | Q12882 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | dihydropyrimidine dehydrogenase |
| 蛋白名全称 | Dihydropyrimidine dehydrogenase [NADP(+)](DHPDHase/DPD) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：DPYD抗体，DPYD多抗，Anti-DPYD Antibody